Diapocynin, a synthetic molecule derived from a naturally occurring compound (apocynin), has been found to protect neurobehavioral function in mice with Parkinson’s Disease symptoms by preventing deficits in motor coordination.The findings are published in the May 28, 2013 edition of Neuroscience Letters, http://www.ncbi.nlm.nih.gov/pubmed/23721786.
Brian Dranka, PhD, postdoctoral fellow at the Medical College of Wisconsin (MCW), is the first author of the paper. Balaraman Kalyanaraman, PhD, Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, chairman and professor of biophysics, and director of the MCW Free Radical Research Center, is the corresponding author.
Funding: This research was funded by NIH grants NS039958 (to B.K.) and NS074443 (to A.K.), and by the Henry R. and Angeline E. Quadracci Chair Endowment (B.K.), and the Eugene and Linda Lloyd Chair Endowment (A.K.).